Tannat—“the healthiest grape”

Mary Malik • July 15, 2025

Polyphenols found in red wine can help fight inflammation and disease, but balance is essential for reaping the rewards.

A cluster of ripe, dark purple grapes hanging on a vine with green leaves and a wooden support post in the background.

For those who enjoy red wines, but a Tannat variety might be a little too much, resveratrol levels are also significant in other choices like Pinot noir, Malbec, Petite Sirah, Cabernet Sauvignon and Merlot. 


Last month we explored the Tannat grape, often called “the healthiest grape” due to its high level of polyphenols. But what are polyphenols and why all the excitement? Once again, Jim Sperk of the Northern Ohio Wine Guild explains.


“Polyphenols are plant-based compounds that contribute to anti-inflammatory and antioxidant effects,” Jim says. “They are not only found in grapes, but also in other fruits, vegetables and in dark chocolate.”


Red wine’s polyphenols originate from the grapes used in its production, with the skin of the grapes a significant source. The maceration process allows for the extraction of these compounds into the wine. Red wine typically contains a higher concentration of polyphenols compared to white wine.


One particular polyphenol, resveratrol, has been shown in studies to inhibit all carcinogenesis stages along with having the potential heart health benefits of protecting the lining of blood vessels and possibly preventing blood clots. Tannat wines have significantly higher levels of resveratrol than practically all other red grape varieties. 


 “That is what makes Tannat the healthiest grape,” Jim says. “As well as offering protection from types of cancers, polyphenols protect against asthma, diabetes, infections, aging and cardiovascular diseases. However, while red wines—Tannat in particular—offer antioxidant and anti-inflammatory benefits, moderation is always key when imbibing in red wine.”


For those who enjoy red wines, but a Tannat variety might be a little too much, resveratrol levels are also significant in other choices like Pinot noir, Malbec, Petite Sirah, Cabernet Sauvignon and Merlot. 


Aside from the obvious risks of excessive drinking, high amounts of polyphenols may also be hazardous to general health.


“This can be a case of ‘too much of a good thing,’” Jim says. “Excessive polyphenol intake can be harmful and lead to things like kidney damage, thyroid imbalances and interfere with the absorption of other healthy minerals such as iron.”



With polyphenols, like other antioxidants, be aware of any potential risks of consuming large quantities and reach out to your doctor with questions. 


For information about the Northern Ohio Wine Guild, contact Jim Sperk at tinymoonwines@usa.net.


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